Bone formation and resorption, respectively, were estimated by serum levels of carboxy-terminal propeptide of type I collagen (PICP) and serum type I collagen carboxy-terminal telopeptide (ICTP).

Results. Eroded cortices of the mandible were significantly associated with increased serum PICP levels (P = .005) in women. Lower mandibular cortical width quartiles were also significantly associated with increased

serum PICP levels in men (P = .020) and women (P = .006).

Conclusions. Mandibular inferior cortical measures detected on Givinostat dental panoramic radiographs may be associated with bone formation rates and be useful in predicting osteoporosis in elderly Japanese men and women. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;108:777-783)”
“The authors describe the demographics, clinical presentation, investigation, treatment, and outcomes of pediatric patients with Guillain-Barre syndrome.

They identified 35 pediatric patients JNJ-26481585 clinical trial with Guillain-Barre syndrome presenting to a tertiary academic center over a 20-year period. The most common presenting symptoms were paresthesias (54%), weakness (49%), and myalgias (49%). Sensation was affected in 54% of patients, and hyporeflexia or areflexia was present in 94% of patients. Cranial nerve dysfunction (46%) and autonomic involvement (eg, changes in blood pressure, pulse, bowel/bladder control, or priapism; 46%) were also common. Autonomic dysfunction, cranial nerve involvement, and albuminocytological dissociation were significantly associated with a decreased time to nadir, the point when symptoms peaked (P = .015, .007, and .005, respectively). Although not statistically significant, treatment with plasmapheresis had a better success rate than intravenous immunoglobulin. The authors’ results will help to further delineate the clinical picture of Guillain-Barre syndrome in children and refine treatment strategies.”
“Structure transformation by heat treatment in single-walled carbon nanotubes

(SWCNT) is investigated using molecular dynamics simulation. The critical temperature for the collapse of pure SWCNT is as high as 4655 K due to strong covalent carbon-carbon bonding. Above 2000 K, the cross section of SWCNT changes from circle to selleck screening library ellipse. The self-repairing capability is then investigated and two efficient processes are observed for the SWCNT to repair themselves. (1) In the first mechanism, vacancy defects aggregate to form a bigger hole, and a bottleneck junction is constructed nearby. (2) In the second mechanism, a local curvature is generated around the isolate vacancy to smooth the SWCNT. Benefit from the powerful self-repairing capability, defective SWCNT can seek a stable configuration at high temperatures; thus the critical temperature for collapse is insensitive to the vacancy defect density. 2010 American Institute of Physics. [doi:10.1063/1.3481004]“
“Objective.