Therefore, the crystalline quality of metamorphic InP is highly i

Therefore, the crystalline quality of metamorphic InP is highly improved in spite of some still existing dislocations. (C) 2014 American Vacuum Society.”
“The calculation of the intrinsic viscosity by means of classical treatments of bead models, typically composed of a number of identical beads, presents some problems when applied to models where the beads are unequal and their number is not very large. A correction to this problem was proposed 10 years ago (Garcia de la Torre and Carrasco in Eur Biophys J 27: 549-557, 1998). This so-called volume correction,

which consisted of adding a term proportional to the volume of the model, was proved to be rigorous in physico-mathemathical terms, and produced improved results in some circumstances, but not always. Recently, the volume correction is being reconsidered Bromosporine so that with some deduced or empirical modifications, it can allow for safer predictions of the intrinsic viscosity. This paper contributes a discussion and further improvements of that correction for the intrinsic viscosity.”
“The paper briefly illustrates several approaches applied in delivering particulate drugs as powders. Micro-particulate drug powders are difficult to manipulate with respect to dosage form preparation, particularly when they have very small size as

this leads to poor flow and packing properties. When the dosage form performance resides in the presence of individual intact drug particles, the particle characteristics have to be retained in selleckchem their original state, i.e., not altered during manufacturing and/or within the dosage form. There are several examples of dry powder dosage forms intended for different administration

routes whose performance is strictly dependent on particle characteristics. In addition, the preparation of the finished dosage form is dependent on powder properties.\n\nThe paper addresses dry powder formulations with special focus on oral powders mainly for elderly people or children, nasal powders and Histone Methyltransf inhibitor inhalation dry powders. These dosage forms are very attractive for both researchers and companies. Their formulation requires deep investigation, mainly in order to define particle structure and performance. Indeed, this makes for a new breakthrough in pharmaceutics and may lead to innovative products. (C) 2012 Elsevier B. V. All rights reserved.”
“Background: A precise approach to the diagnosis of von Willebrand disease (vWD) remains elusive. One important reason is that vWD is a blood flow-related disorder: a vW Factor-platelet GPIb binding defect exists in this condition under the high shear-rate (> 1000 sec-1 inwhole blood; > 3000 sec-1 in PRP) conditions of physiologic blood flow which exist in the arterioles of mucous membranes, from which most bleeding in vWD occurs.\n\nMethods: We therefore studied 28 patients (mean 18.

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