The last section aimed to assess the knowledge best of the respondents. At the end of each interview, the parents were counseled on the need and positive aspects of vaccination, and attempts were made to shun any false beliefs. Hence, our study not only provided exploratory analysis, but also served as a didactic tool. Analysis of data Data from the questionnaire was entered in SPSS (Statistical Package for Inhibitors,Modulators,Libraries the Social Sciences) version 17 for analysis and the results were compared. Descriptive statistics formed the mainstay of the statistical analysis. P values were calculated to determine the significance of association between variables and were based on the Chi-square test. Continuous variables such as age were converted into categorical ones. A P value of less than 0.05 was considered to be significant.
Characteristics that were found to be significantly Inhibitors,Modulators,Libraries associated with vaccination status were entered into a multivariate logistic regression model. Vaccination status was converted into a dichotomous variable (vaccinated vs. under-vaccinated), and was used as the dependent variable for the regression model. Results Demographics A total of 1044 out of 1200 parents approached agreed to the interview, giving a response rate of 87.0%. The mean age of the patients was 4.8��2.9 years. 553(53.0%) patients were female, whereas 491(47.0%) were male. 969(92.8%) had both parents who were alive, whereas 34(3.3%) had only the mother alive, and 41(3.9%) had only the father alive. Measles (9.2%) was the most common previously contracted VPD, followed by Hepatitis B (6.4%), pertussis (3.
6%), tuberculosis (1.8%) and polio (0.3%). The mean maternal and paternal ages were 28.7 �� 4.1 years and 33.4��5.9 years respectively. The mean number of years since marriage was 9.8��4.7 years, with each couple having an average of ~3 children. The socioeconomic status of majority Inhibitors,Modulators,Libraries was low, with the mean household income being Rs. 7823.5��2941.8 (~USD 80��30). Table 2 gives a summary of the parent demographics. Table 2 Demographics of parents at two tertiary care centers in Karachi, Pakistan from 4th January, 2012 to 6th January, 2013 and the association with the vaccination status Vaccination status Out of 1044 patients, only 713(68.3%) were fully vaccinated, 239(22.9%) were partially vaccinated while 92(8.8%) had never been vaccinated. Figure 1 gives a Inhibitors,Modulators,Libraries graphical representation of this data.
Out of those who were partially vaccinated, 107(44.8%) had not received the full course of Oral Polio Vaccine, and 51(21.3%) did not have a BCG scar. The vaccination status showed statistically significant association with ethnicity, income, residence, number of children and paternal occupation (p<0.05 Inhibitors,Modulators,Libraries for all). However, no significant association was found with maternal or paternal education status (p>0.05 for both). The significant variables were subjected Entinostat to multivariate logistic regression analysis.