\n\nSTUDY DESIGN AND METHODS: National data gathered between March 2004 and October 2010 from 12 CBS sites were analyzed to compare bacterial contamination rates across three platelet (PLT) preparation methods: apheresis, buffy coat, and PLT-rich plasma. Data were compared before and after implementation of protocol changes that may affect bacterial detection or contamination rates.\n\nRESULTS: Initial positive Selleckchem CX-6258 rates among the

three production methods were significantly different, with apheresis PCs being the highest. The rates of confirmed positives among production methods did not differ significantly (p = 0.668). Increasing sample testing volumes from 4 to 6 mL to 8 to 10 mL significantly increased the rate of initial positives, Selleck BVD-523 while confirmed positives increased from 0.64 to 1.63 per 10,000, approaching significance (p = 0.055). Changing

the skin disinfection method from a two-step to a one-step protocol did not significantly alter the rate of confirmed positives. During the period of data analysis, eight false-negative cases were reported, with five implicated in adverse transfusion reactions.\n\nCONCLUSION: Bacterial testing of PCs and implementation of improved protocols are incrementally effective in reducing the risk of transfusion of bacterially contaminated PLT concentrates; however, the continued occurrence of false-negative results means the risk has not been eliminated.”
“Herpes folliculitis is a rare manifestation of herpes virus infection. It usually represents

a diagnostic challenge, due to the I-BET-762 chemical structure absence of characteristic skin manifestations such as vesicles or pustules. The reported cases are mainly associated with varicella zoster virus (VZV) and less commonly with herpes simplex viruses (HSV-1 y HSV-2). We report a 51-year-old male with a relapsing non-Hodgkin Lymphoma under chemotherapy, with history of extensive follicular lesions lasting one month. The pathologic study of the lesions was consistent with necrotizing herpes folliculitis. The patient was treated with Valacyclovir, achieving remission of the lesions. The appearance of folliculitis, especially in an immunocompromised patient, should raise the suspicion of herpes virus infection. Polymerase chain reaction may help to elucidate the diagnosis when pathologic findings are non-specific. (Rev Med Chile 2012; 140: 1589-1592).”
“It was aimed to determine energetic and amino acidic composition, coefficients of metabolizity of energy and digestibility of viscera meal for poultry. The method of forced feeding with cecectomized adult cockerel was used. A completely randomized design was used, with 4 different viscera meals (3 of poultry, one from swine, and one in fast), six replications and one cecectomized cockerel per experimental unit.