Results: During the course of chemotherapy, the most common adverse reactions were nausea, vomiting, neurotoxicity and phlebitis. Bone marrow suppression occurred relatively less. There were no significant statistical differences between male and female. Conclusion: The toxicity and side effects of Oxaliplatin based chemotherapy Idasanutlin purchase are mainly nausea and vomiting, followed by neuron toxicity and phlebitis, and relatively less for bone marrow suppression. Proper nursing intervention can decrease the frequency and severity of these side effects. Key Word(s): 1. adverse reactions;

2. nursing care; 3. Oxaliplatin; 4. observation; Presenting Author: LIAOLIAO XIN Additional Authors: MEIXIA WANG, LI HE, FENXIA LIU, MEIXIU LIU, JING ZHANG, ZHIJUAN YANG Corresponding Author: LIAOLIAO XIN Affiliations:

Xijing Hospital of Digestive Diseases Objective: To compare the effects of central venous catheter with superficial vein indwelling needle for tumor patients with long-term chemotherapy. Methods: we recruited 31 patients with central venous catheters and 208 patients with superficial vein indwelling needles in our department between January and March of 2013 into 2 groups based on their admission time. Comparison was made by observing the leakage, redness, induration, pain, phlebitis, pigmentation, and their chief complaints. Results: Patients with PICC felt that they benefited from it in their daily life, such as avoiding inconvenience during taking meals and using the toilet. More importantly, PICC reduced the pain brought by avoiding multiple puncture, and damaging blood vessels in the infusion process no pigmentations selleck was reported on the skin by chemo drugs. On the other hand, patients Farnesyltransferase with superficial vein indwelling needles had to be observed regularly in the puncture area, which increased the burdens of nurses. As Long-term chemotherapy damaged blood vessels, it made more difficult for nurses to do the puncture. Some patients suffered from the pigmentations on the skin along the puncture area after infusion. In comparison, the effective rate of using PICC is 90.3%, while the superficial vein-indwelling needle

is 48%. Conclusion: For Patients with Long-term chemotherapy, using PICC is safer, more effective, reduces pain, and protects blood vessels well with fewer complications. Therefore, PICC is significantly better than the superficial vein-indwelling needle. Key Word(s): 1. PICC; 2. indwelling needle,; 3. safety; Presenting Author: MEIXIU LIU Additional Authors: MEIXIA WANG, LIAOLIAO XIN, FENXIA LIU, PEI QIN, JING ZHANG, LI HE Corresponding Author: MEIXIU LIU Affiliations: XiJing Hospital of Digestive Diseases Objective: To explore the value of Pain Intervention by nursing For Gastric Cancer Patients with Peritoneal Metastasis. Methods: Nursing guidance was offered to 58 gastric cancer patients with peritoneal metastasis suffering from pain in the course of treatment.