“
“A preliminary case-control study.
To assess postural control in individuals with and without non-specific chronic low back pain (cLBP) during quiet Elafibranor ic50 standing.
cLBP affects 12-33 % of the adult population. Reasons for pain chronicity are
yet poorly known. Change in postural control may be a risk factor for cLBP, although available studies are not conclusive.
Sample consisted of 21 individuals with cLBP and 23 controls without cLBP. Balance was assessed using a force plate (Balance Master(A (R)), NeuroCom) by the modified clinical test of sensory interaction and balance, pain severity by the visual analogue scale, quality of life with the SF-36 Questionnaire, and functional disability with the Roland-Morris Questionnaire.
Groups were homogeneous for age, weight, height and body mass index. Relative to
controls, participants in the cLBP group had deficits IWP-2 in vivo in the postural control, with greater postural sway in the quiet standing condition with closed eyes closed on unstable surfaces (p < 0.05) for the following parameters: total COP oscillation [cLBP 1,432.82 (73.27) vs CG 1,187.77 (60.30)], root mean square sagittal plane [cLBP 1.21 (0.06) vs CG 1.04 (0.04)], COP area [cLBP 24.27 (2.47) vs CG 16.45 (1.79)] and mean speed of oscillation [cLBP 12.97 (0.84) vs CG 10.55 (0.70)].
Postural control, as evidenced by increased oscillation of COP, is impaired in individuals with learn more cLBP relative to controls. Differences
are magnified by visual deprivation and unstable surface conditions.”
“The solubilities of losartan potassium in eight solvents; 1,4-dioxane, acetonitrile, propylene glycol, N-methyl-2-pyrrolidone, 1-butanol, 1-hexanol, 1-heptanol, and 1-octanol, were measured at temperatures ranging from 293.2 to 318.2 K at atmospheric pressure using shake-flask method of Higuchi and Connors. N-methyl-2-pyrrolidone dissolved the highest amount of losartan potassium and 1,4-dioxane possessed the lowest solubilization power among the investigated solvents. The generated data was used to calculate the thermodynamic parameters of the system using the modified van’t Hoff equation and the Gibbs free energy data was correlated using Abraham solvation parameters.”
“The aim of this study is to evaluate the prevalence and severity of low back pain (LBP) and the influence of sciatica and neurological deficits in old men.
Mister osteoporosis Sweden includes 3,014 community-dwelling men aged 69-81 years. At study start 3,009 participants answered questions on LBP, low back pain and sciatica (LBP + SCI) or low back pain and sciatica with associated neurological deficits (LBP + SCI + NEU) during the preceding 12 months. Data are presented as proportions or medians with mid-quartile ranges. Differences between groups were tested by chi(2) test and Kruskall-Wallis test.
24 % had experienced LBP without SCI, 8 % LBP + SCI and 14 % LBP + SCI + NEU.