8 eV) with the increase in temperature in all these metallic films. The rapid decrease in conduction band polarization in the film on LAO has strong implications for the use of these manganites in room temperature spintronics. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3062820]“
“Objective: Emotional distress (ED) is an under-diagnosed problem in cancer patients and over the last decade a number of national guidelines have recommended an assessment and management model based on appropriate health professional response to a hierarchy of patient need. This study explores the views of cancer LY2090314 in vivo professionals regarding their current roles

and responsibilities in the detection and management of ED, use of screening tools and access to expert psychological support.

Methods: Interviews with 23 professionals were conducted

[6 clinical nurse specialists (CNS), 8 oncologists, 4 surgeons and 5 ward sisters] from hospitals in Yorkshire, UK. Data were evaluated using framework analysis.

Results: Detection of ED was seen to be the responsibility of the whole cancer team though nurses, particularly CNSs, are heavily depended upon to assess and manage distress. Experience of screening tools was limited and a number of reservations were this website expressed about routine implementation. A wide range of services are used to support distressed patients but a lack of referral guidance and access to specialist psychological care were reported to be a significant barrier to effective management.

Conclusions: Cancer professionals describe working within HER2 inhibitor the fundamental principles of the guidance frameworks; however, access to specialist support do not appear to meet recommendations, leaving the CNS with considerable responsibility for the detection and management of ED. Support for ED may be improved by the introduction of routine screening along with appropriate training and implementation

of referral guidelines to assist professionals in accessing specialist psychology services. Copyright (C) 2011 John Wiley & Sons, Ltd.”
“Purpose of reviewThe mechanisms of tolerance induction and maintenance remain incompletely understood and have yet to be translated to clinical practice. Advances in imaging techniques have allowed precise examination of cell interactions in the lymph node, often in real time. Herein we review evidence that lymph node structure is dynamic and controls the character of the immune response in a multistep, multiplayer dance. T-cell responses in particular can be initiated or influenced in regions beyond the canonical T-cell zone. We propose that the cortical ridge is one such region required for induction and maintenance of tolerance.Recent findingsLymph node domains are more complex than T-cell and B-cell zones. Different domains are important for different types of immune responses.