5116 1min vs 372 5 +/- 58 7min, P=0 03) and worse SE (59 2

5116.1min vs. 372.5 +/- 58.7min, P=0.03) and worse SE (59.2 Adavosertib manufacturer +/- 22.7% vs. 75.9 +/- 11.2%, P=0.04) when compared to participants with 2-3 episodes of nocturia with low bother (n=13).

ConclusionsThese results verify objectively that PD patients with nocturia have poor sleep. Furthermore, among individuals with comparable levels of reported nocturia, higher bother is associated with poorer sleep as defined on PSG. Neurourol. Urodynam. Published 2013. This article is a U.S. Government work

and is in the public domain in the USA. Neurourol. Urodynam. 32:1080-1085, 2013.”
“Aim: Grief and its many manifestations can irrevocably change family life and the multiple relationships within. Informed by this, one is led to consider the extent an adult

nurse provides a family focus to cancer care. It arguably remains wanting, particularly in adult healthcare environments where ‘family’ can still infer ‘spouse’ and the needs of children and young people at home may as a result go unrecognized. Little attention has been paid to what or how young people should be told about their parent’s cancer diagnosis, but from the limited research that has been undertaken, parents are seeking help with this aspect of communication.

Methods: An interpretative phenomenological approach was used to explore the research question: How do young people experience learning about their parent’s cancer diagnosis? This was a single

centre study PCI32765 recruiting seven participants, aged 14-18 years, which LY2109761 included two sets of siblings. Participants were interviewed on one occasion only.

Results: The interview data revealed six dimensions of the young person’s experience of learning about a parental diagnosis: first hearing about a parent’s diagnosis; vulnerability of self and others, communication within the family, feeling supported in experience, experience and support of school, experience and support of hospital. Young people overwhelmingly advocate honesty and openness in family communication about cancer.

Conclusions: Our participants demonstrated strength and resourcefulness in adapting to their parent’s cancer. Meaning making was central to our study’s intent and still today it offers a perspective of the diagnosis period that has not been fully explored in the extant literature. (C) 2009 Elsevier Ltd. All rights reserved.”
“Objective: Since young women undergoing cyclophosphamide pulse therapy may suffer premature ovarian failure (POF) in almost 50% of cases, we examined the ability of GnRH-a administration to minimize the gonadotoxicity associated with cyclophosphamide pulse therapy (CPT).

Methods: Retrospective analysis of medical charts of 44 women (age 16-38 years) who received CPT for autoimmune diseases. In 33 patients a monthly depot injection of GnRH-a was started before the alkylating agent.

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