Improving muscle strength may thus be an important intervention strategy in reducing falls. The study showed that the fall incidence in the Tai Chi group was lower than in the stretching group, but was similar to the resistance training group. Although improvement in postural control may explain the reduction in fall rate, the muscle strengthening effect of Tai Chi may also contribute, as the Tai Chi training OTX015 nmr induced gain in knee muscle strength that is comparable to resistance exercise training. In this study, all patients with a Mini-Mental State examination score < 24 were excluded, but a proportion of patients with Parkinson's disease suffer

from mild cognitive impairment and dementia. Tai Chi BAY 73-4506 clinical trial is a mind-body exercise and the practice of Tai Chi may enhance cognition and dual-task performance (Tsang et al 2012). Future study should address the effect of Tai Chi on these important outcomes, and their relationships with fall incidence in patients with Parkinson’s disease, including those with cognitive impairment. “
“Summary of: Belardinelli R, et al (2012) 10-year exercise training in chronic heart failure.

J Am Coll Cardiol 60: 1521–1528. [Prepared by Nora Shields, CAP Editor.] Question: Does aerobic exercise improve peak VO2, quality of life, all-cause mortality, and cardiovascular morbidity in patients with chronic heart failure with mild to moderate symptoms? Design: Randomised, controlled trial with blinded outcome assessment. Setting: Hospital and community settings in Italy. Participants: Patients with chronic heart failure who were clinically stable, had a left ventricular ejection fraction < 40%, and the ability to exercise. Haemodynamically significant valvular heart disease, uncontrolled diabetes or hypertension, and renal insufficiency were exclusion criteria. One hundred and thirty-five patients enrolled in the study and 123 completed the protocol. Randomisation of 123 participants (78% male) allotted 63 to the exercise group nearly and 60 to a usual care group. Interventions: Both groups received counselling on smoking cessation, stress reduction and diet. In addition, the intervention group participated in an exercise training program

for 10 years. The program consisted of 3 × 1-hour sessions per week of aerobic exercise at 60% peak VO2 at a hospital for 2 months under the supervision of a cardiologist and an exercise therapist, and 2 supervised 1-hour sessions at 70% peak VO2 the rest of the year in a community setting. Patients were also encouraged to exercise at home at least once a week. Each exercise session included 40 minutes of aerobic activity (cycling and treadmill). The control group received usual care and were advised to continue their usual physical activities for no longer than 30 minutes each session. Outcome measures: The primary outcomes were functional capacity, measured by peak VO2 as a percentage of predicted maximum VO2, and quality of life over 10 years.