millerae 97.9 2 0 4 31 5 42 9 Mbr. millerae 97.9 10 4 4 11 2 31 10 Mbr. millerae 99.8 4 1 12 0 14 31 11 Mbr. MLN4924 cost smithii 98.1 5 9 3 4 4 25 12 Mbr. millerae 97.9 0 19 3 0 2 24 13 Msp. stadtmanae 96.4 3 3 0 2 9 17 14 Mbr. smithii 98.0 6 1 4 5 0 16 15 Apr. boonei 82.3 0 0 9 0 0 9 16 Mbr. ruminantium 96.4 3 2 1 0 1 7 17 Mbr. millerae 98.7 3 0 2 0 2 7 18 Apr. boonei 82.5 0 0 1 1 4 6 19 Mba. alcaliphilum 95.5 1 1 2 1 0 5 20 Mba. alcaliphilum 96.5 0 4 1 0 0 5 21 Mbr. olleyae 96.7 0 1 0 3 1 5 22 Msp.

stadtmanae 96.5 0 0 1 4 0 5 23 Mbr. millerae 97.2 1 0 1 2 0 4 24 Mba. alcaliphilum 96.9 1 0 0 0 3 4 25 Mbr. ruminantium 98.4 0 1 1 0 1 3 26 Mbr. ruminantium 97.7 0 2 1 0 0 3 27 Mbr. smithii 97.3 0 1 1 1 0 3 28 Apr. boonei 82.6 0 0 2 1 0 3 29 Mbr. millerae 97.3 2 0 0 0 0 2 30 Mbr. p38 MAPK inhibitors clinical trials millerae 97.8 2 0

0 0 0 2 31 Apr. boonei 81.6 0 2 0 0 0 2 32 Mbr. ruminantium 97.5 0 1 0 1 0 2 33 Mbr. ruminantium 97.2 0 1 0 0 1 2 34 Mbr. ruminantium 95.6 0 0 1 1 0 2 35 Apr. boonei 81.7 0 0 1 0 1 2 36 Mbr. gottschalkii 96.4 0 0 0 0 2 2 37 Mbr. gottschalkii 96.7 1 0 0 0 0 1 38 Apr. boonei 80.9 0 1 0 0 0 1 39 Mbr. ruminantium 96.4 0 1 0 0 0 1 40 Mbr. ruminantium 94.8 0 1 0 0 0 1 41 Mbr. wolinii 95.8 0 1 0 0 0 1 42 Mbr. millerae 97.2 0 0 1 0 0 1 43 Mbr. of unique OTUs % OTU coverage Shannon Index ± 95% confidence limits LIBSHUFF selleck chemicals llc Methodc Alpaca 4 3 97.8 2.06 ± 0.15b P≤ 0.0004 Alpaca 5 5 93.5 2.12 ± 0.14b P≤ 0.0022 Alpaca 6 2 94.0 1.96 ± 0.15b P≤ 0.0001 Alpaca 8 3 95.2 1.89 ± 0.16b P≤ 0.0028 Alpaca 9 6 94.4 2.09 ± 0.17b P≤ 0.0028 Combined – 98.4 2.85 ± 0.07b – a Schloss et al. the comparison of Alpaca 4 against Alpaca 5, Alpaca 6, Alpaca 8, and Alpaca 9 was always significantly different P ≤ 0.0004) We found that 37 OTUs, representing 88.3% of clones isolated from our combined libraries, displayed 95% or greater RG7112 genus-level sequence identity to species belonging to Methanobrevibacter, making it the dominant genus in the microbial community of the alpaca forestomach (Table 3).